Polymyositis, Meet Methotrexate

Five weeks of prednisone managed to improve the polymyositis by 40 percent (as measured by the reduction of the key creatine protein kinase - CPK - enzyme level rheumatologists enjoy tracking). While that's good, I'm tired of triggering a 110-beat heart rate every time I climb a flight of steps.

So, last week I introduced my immune system to methotrexate, per the rheum doc's recommendation. Basically the regiment is to take a dose once a week. I began the methotrexate treatment on Wednesday.

Saturday I dismantled detritus wood from the deck that needed to be replaced. We bought a new spa (the original that came with the house didn't hold water), and it's shape was slightly different than the old one. Then I went to Lowe's and loaded a lumber cart with a few joists and treated planks, unloading everything upon arriving home. Sunday saw me bowling and moving furniture, including schlepping couches down a flight of steps and a futon and thick-and-heavy mattress up a flight. Then I worked a 15-hour day Monday. All this without ill effects. Obviously, that's improvement.

I don't believe methotrexate works that fast. I've read it takes three weeks to hit its stride. If the conventional protocol proves effective in my case, though, the new energy and strength I'm feeling is likely a very good sign.

If the current strength trend continues, I may have to dust off the single speed for a simple coffee ride.